The three periods in which physiological Gynecomastia is in newborns occur during or before puberty, and in old age. The causes for this disease are unclear, and there is no clear cause. Some of the potential culprits appear to be drugs, including hormones, an increase in serum estrogen, a decline in testosterone production, androgen receptor defects, chronic renal disease, chronic liver disease, HIV, and in some other chronic diseases. There were also cases of gynecomastia occur as a result of an injury to the spinal cord and even after refeeding famine victims. But in 25% of all cases of gynecomastia, the matter is simple unknown.
In post-adolescent adults is of the opinion that 10-20% of all cases of gynecomastia are a direct result of drugs. Some of the drugs can cause gynecomastia are cimetidine, spironolactone, omeprazole, imatinib mesylate, finasteride, and some antipsychotics. With leading to increased release of prolactin from the pituitary from the blocking of the actions of dopamine on the cell in the anterior pituitary lactotrope known as the development of the male breast is possible. Other drugs such as for the treatment of prostate cancer and how antiandrogens GnRH analogues are also thought that the cause Gynecomastia.
Another cause is thought to have the use of marijuana gynecomastia, although published data contradicts this assertion. It is also possible that increased estrogen levels may take place in some testicular tumors, as well as hyperthyroidism. Some adrenal tumors can cause elevated androstenedione, which is then converted into estrone, a form of estrogen, by the enzyme aromatase. All other forms of tumors that secrete hCG estrogen can also increase as well. In cirrhosis, a decrease of estrogen clearance can occur by many to gynecomastia. The reason obesity may cause gynecomastia is also in the fact that it increases estrogen levels.
In a recent study, we found that the repeated use of products with tea tree oil and lavender, as well as several other unidentified substances may associated with the development of gynaecomastia in prepubescent males. The theory behind this is that the ingredients to produce estrogen and antiandrogenic activity. With this said, there were other circumstances, and the study was Stichprobengrae to three persons, therefore, no real scientific conclusions could drawn.
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